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How Xarelto Causes Internal Bleeding
XARELTO CAN CAUSE INTERNAL BLEEDING
Xarelto bleeding can happen because the drug doesn’t distinguish between which clots are dangerous and which ones are beneficial. It’s mechanism prevents all blood clots from forming. Without a way to stop excessive bleeding, this can become life threatening.
XARELTO PREVENTS BLOOD CLOTS
When the body is damaged it defends itself from excessive bleeding by forming a blood clot as the initial step in tissue repair. Damaged tissue releases chemicals that initiate the series of reactions leading to clot formation, and factor Xa is a key component of that process.
NO KNOWN XARELTO REVERSAL
Because Xarelto inhibits factor Xa, it impairs the development of beneficial clotting that would reduce bleeding. As there is no effective way to counteract Xarelto, this means that once an individual starts bleeding, it is very difficult to stop.
There Is No Xarelto Antidote Or Reversal
Xarelto currently does not have an approved reversal agent and as a result individuals taking taking this drug are at higher risk for excessive bleeding. Without an antidote, it is extremely difficult to immediately stop any internal bleeding.
Xarelto Vs Warfarin
Xarelto has increased bleeding risk over Warfarin. Xarelto works by binding itself to proteins in the blood. Because of its strong bond to those proteins, Xarelto cannot be removed by dialysis. As there is no reversal for the effects of Xarelto, it will continue to inhibit clot formation until the drug is broken down or excreted.
Warfarin does not have the same bleeding risk that Xarelto has. Warfarin acts by reducing the amount of the clotting substance, vitamin k, in the blood. In the event of bleeding, Warfarin can be counteracted by administering more vitamin K to increase its concentration in the bloodstream, and it can also be effectively removed by dialysis.
Damage from Excessive Bleeding
Our blood is responsible for carrying nutrients (primarily oxygen) to the tissues throughout our body. Any reduction in blood volume reduces the ability to provide nutrients to our tissues and can result in tissue injury or tissue death. In cases of severe blood loss it can lose the ability to effectively pump blood at all – this is known as hypovolemic shock – and lead to heart attack and/or stroke. In the case of a cut, laceration, nosebleed, etc. this bleeding is visible, but excessive bleeding can occur internally as well with the same dangerous effects.
|General tissue injury||Damage to vital organs||Heart attack|
|Stroke||Death||Heart and brain damage|
|Permanent disabilities / impairments|
Many people have been seriously injured from uncontrollable bleeding while taking Xarelto. Since the manufacturer did not discover an effective reversal agent before releasing Xarelto to the market, those who were injured have filed lawsuits claiming that Bayer:
- Marketed Xarelto as a safe alternative to other blood thinners while hiding potential risks
- Failed to warn consumers of potential dangers
- Did not thoroughly investigate an effective way to stop bleeding for Xarelto before releasing it to the market
- Put company profits ahead of public safety